Our business venture aims to develop and commercialize Point-Of-Care Testing (POCT) devices for molecular diagnostics. We have invented a low-cost and simple semiconductor based real-time nucleic acid amplification detection device. We are employing the pH sensing biosensor in place of the currently used fluorescence based Real-time PCR systems which are very expensive and need special technical expertise to work with. This can indicate the presence/absence of pathogens; determine concentration of pathogens or gene of interest and specific states of pathological conditions of the body.
Our primary focus will be in developing and commercializing a POCT device with the ability of performing single tests and panel tests (around ten to twenty tests). Single tests like Tuberculosis bacilli (TB) or multidrug resistant TB, Malaria, Hepatitis B Virus (HBV), etc. can be done using single test chips. Multi-test panel chips can be used for applications like testing ‘donated blood’ for different pathogens like HIV, Hepatitis B Virus, etc. wherein the biosensor chip will contain multiple sensors and can take a single input sample for conveniently testing for presence of required pathogens in one run.
FIB-SOL aims to develop efficient carrier systems for biofertilizers. Liquid bio fertilizers (LBF) and Fertilizer carrying membrane (FCM) are the two products developed at FIB-SOL, which, comprises of microbial formulations with improved stabilizers and carrier material. The products are aimed at improving the storage, application and logistics of bio fertilizers compared to currently available products. Currently FIB-SOL has developed a liquid formulation (N-SOL 20) and a fibre based carrier formulation (N-FIB 20), which is applicable to non-leguminous crops like paddy, cotton, vegetables, fruits and tea plantations. The products are indigenous and would cut cost due to import of fertilizers, improve logistics and promotes organic farming.
Vital Bioscientific Solutions is a private limited company registered under Companies Act 2013. It is a spin off by research scholars from Departement of Biotechnology , IIT Madras and is presently incubated at the IIT Madras Incubation Cell. Drug discovery is a multi-step process, which is broadly divided into the initial discovery phase, followed by a validation phase, spanning decades of research and development prior to a successful market launch of a drug.An average $802 million is spent on every newly launched drug and the major determinants of this elevated cost are the high attrition rate of a large pool of candidate molecules in the discovery phase and the R&D involved in short listing then for the validation phase. Despite the efficacy of a candidate molecule, its ADMET properties (Absorption-Distribution-Metabolism-Excretion-Toxicity) determine its fate. Hence the interest of major players is in developing economically viable strategy for screening the new and existing candidate molecules for favorable ADMET properties. Current focus of the company is to develop novel products and services for efficient screening of NCEs and drugs in pre-clinical studies.
Yaathum Biotech (YB) was started in November 2012 by four young students who have done their Masters in Biomedical field in UK, with the aim of indigenously developing Real-time quantitative PCR (qPCR) kits for rapid /affordable diagnostic testing and research purposes. Our current venture is to develop and market multiplex qPCR based diagnostic test kit that would make possible the identification of full range of Drug Resistant Tuberculosis (DR-TB) at one third the present cost, taking a few hours to test and capable of identifying all MDR and XDR-TB strains in a single test which is not available at present. We have collaborative support from National Institute for Research in Tuberculosis (NIRT), Chennai, M.S. Swaminathan Research Foundation (MSSRF), Chennai and Foundation for Innovation and Technology Transfer (FITT), IIT Delhi. We also currently provide research services for customers in universities, academic institutions and industries, in multiple areas of biotechnology - medicine, food, agriculture based on cutting edge technologies like Real-time quantitative PCR and DNA Sequencing/NGS.